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Research use only. Not for human or veterinary use. €200 minimum order
For research use only. Products sold by Peptide Shop are intended for in-vitro laboratory research only. Not for human or veterinary diagnostic, therapeutic, cosmetic or consumption purposes.
LL-37, human cathelicidin — 1 mg, ≥98 % HPLC product vial
Immunology

LL-37, human cathelicidin — 1 mg, ≥98 % HPLC

>- Human cathelicidin LL-37 antimicrobial peptide, the gold-standard innate-immunity reference. ≥98% HPLC. RUO.

≥ 98% COA supported RUO
CAS
154947-66-7
Molecular weight
4493.33 g/mol
Storage
-20°C lyophilised, desiccated, protected from light (research only)
Package sizes
1 × 1 mg vial

Description

LL-37, human cathelicidin — 1 mg, ≥98 % HPLC — research overview

LL-37 is the only human cathelicidin antimicrobial peptide, derived by proteolytic cleavage of hCAP-18. It is the most widely cited reference compound in antimicrobial-peptide and innate-immunity research.

Peptide Shop supplies LL-37 (1 × 1 mg vial) as a sealed research material with lot-level documentation. This product is supplied for in-vitro laboratory research only and is not intended for human use, veterinary use, therapy, diagnosis, cosmetic application or consumption.

Research applications

  • Antimicrobial peptide (AMP) research and MIC determination
  • Innate-immunity and host-defence studies
  • Endotoxin (LPS) neutralisation research
  • Wound-closure and re-epithelialisation assay models
  • Inflammation, chemotaxis and biofilm-disruption assays

Sequence and analytical data

Identity confirmed by ESI-MS ([M+H]+ = 4494.3). Highly cationic and amphipathic; uses low-binding tubes recommended.

Storage and handling

Store lyophilised at -20 °C protected from light. Reconstitute in sterile water or 0.01% acetic acid; avoid contact with serum proteins which bind LL-37 strongly.

Documentation

A lot-specific Certificate of Analysis is available in EN, DE, FR and ES from the product detail page after dispatch. The CoA reports HPLC purity, identity confirmation, appearance, and storage and handling guidance for the dispatched lot.

Sequence & data

Product IDpeptide-ll-37
CAS154947-66-7
Molecular weight4493.33 g/mol
Purity≥ 98%
SequenceLLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES

Storage & handling

-20°C lyophilised, desiccated, protected from light (research only)

Keep lyophilised material sealed and protected from moisture. Reconstituted materials should be handled according to validated laboratory protocols and disposed of as research waste.

Certificate of analysis

Batch-specific COA documentation is supplied according to the COA policy and may include HPLC purity, identity and lot information where available.

Other languages

FAQs

Why is LL-37 considered the AMP reference?

LL-37 is the only human cathelicidin and one of the most extensively published AMPs, making it the de-facto positive control in antimicrobial-peptide research.

Should I use low-binding tubes?

Yes — LL-37 is highly cationic and adsorbs strongly to standard polypropylene. Low-protein-binding tubes are strongly recommended for reproducible activity.

Is the C-terminus amidated?

No, LL-37 has a free C-terminal carboxylate, matching the natural cleavage product of hCAP-18.