Description
TB-500 (Thymosin β4 frag.) research overview
TB-500 thymosin beta-4 fragment for cell-migration, actin and angiogenesis research. ≥99% HPLC purity with COA. RUO.
TB-500 is a synthetic thymosin beta-4 fragment studied for actin regulation, cell motility, angiogenesis and inflammatory-response models.
Peptide Shop supplies TB-500 (Thymosin β4 frag.) as a sealed research material with lot-level documentation where available. This product is supplied for in-vitro laboratory research only and is not intended for human or veterinary diagnostic, therapeutic, cosmetic or consumption purposes.
Research use
- Cell-migration and scratch-wound assays
- Angiogenesis and endothelial-cell models
- Comparative cell-migration studies with BPC-157
Often evaluated as a reference peptide in cell-migration and extracellular-matrix workflows.
Sequence and analytical data
| Field | Detail |
|---|---|
| Product ID | peptide-tb-500 |
| Package size | 1 × 5 mg vial |
| CAS number | 77591-33-4 |
| Molecular weight | 4963.5 g/mol |
| Purity | ≥ 99% |
| Storage | -20°C recommended (research-only) |
Batch-specific documentation may include HPLC purity, identity confirmation and lot information. Refer to the supplied COA or the COA policy for current documentation scope.
Reconstitution and handling
Allow lyophilised material to equilibrate before opening to reduce condensation risk. Add validated solvent slowly down the vial wall, avoid vigorous shaking, and record the final concentration in the laboratory notebook or LIMS.
Use aseptic technique, calibrated pipettes or syringes, and validated diluent choices for the assay system. Reconstituted materials should be aliquoted where appropriate to reduce repeated freeze-thaw exposure.
Storage
Store unopened material according to the stated condition: -20°C recommended (research-only). Keep vials sealed, dry and protected from light. Reconstituted solutions should be stored under validated laboratory conditions and discarded according to internal SOPs and applicable research-waste rules.
Related resources
Research-use statement
TB-500 (Thymosin β4 frag.) is sold by Peptide Shop for research use only. It is not a medicine, food, cosmetic, supplement or diagnostic product. Buyers are responsible for ensuring lawful purchase, storage, handling and disposal under their institutional and local requirements.
References
- Goldstein AL et al. “Thymosin beta4: a multi-functional regenerative peptide. Basic properties and clinical applications.” Expert Opin Biol Ther. 2012;12(1):37–51. PMID 22128900
- Ho EN et al. “Doping control analysis of TB-500, a synthetic version of an active region of thymosin β₄, in equine urine and plasma by liquid chromatography–mass spectrometry.” J Chromatogr A. 2012;1265:57–69. PMID 23107195
- Sosne G et al. “Thymosin beta 4 and the eye: the journey from bench to bedside.” Expert Opin Biol Ther. 2015;15 Suppl 1:S147–56. PMID 26305390
- Bock-Marquette I et al. “Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair.” Nature. 2004;432(7016):466–472. PMID 15565145
- Smart N et al. “Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization.” Nature. 2007;445(7124):177–182. PMID 17108969
