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Research use only. Not for human or veterinary use. €200 minimum order
For research use only. Products sold by Peptide Shop are intended for in-vitro laboratory research only. Not for human or veterinary diagnostic, therapeutic, cosmetic or consumption purposes.
Tesofensine 5 mg — research compound product vial
Neuroscience & CNS

Tesofensine 5 mg — research compound

Tesofensine research compound for monoamine transporter and metabolic CNS studies. COA supplied. RUO.

≥ 99% COA supported RUO
CAS
402856-42-2
Molecular weight
382.5 g/mol
Storage
Room temperature, protected from light
Package sizes
60 × 0.5 mg caps

Description

Tesofensine 5 mg research overview

Tesofensine research compound for monoamine transporter and metabolic CNS studies. COA supplied. RUO.

Tesofensine is a monoamine reuptake inhibitor reference compound studied in transporter, appetite and CNS-metabolic models.

Peptide Shop supplies Tesofensine 5 mg as a sealed research material with lot-level documentation where available. This product is supplied for in-vitro laboratory research only and is not intended for human or veterinary diagnostic, therapeutic, cosmetic or consumption purposes.

Research use

  • Dopamine, noradrenaline and serotonin transporter research
  • Appetite and energy-balance models
  • CNS-metabolic pathway studies

Relevant to metabolic and neuroscience research navigation.

Sequence and analytical data

FieldDetail
Product IDpeptide-tesofensine
Package size60 × 0.5 mg caps
CAS number402856-42-2
Molecular weight382.5 g/mol
Purity≥ 99%
StorageRoom temperature, protected from light

Batch-specific documentation may include HPLC purity, identity confirmation and lot information. Refer to the supplied COA or the COA policy for current documentation scope.

Reconstitution and handling

Allow lyophilised material to equilibrate before opening to reduce condensation risk. Add validated solvent slowly down the vial wall, avoid vigorous shaking, and record the final concentration in the laboratory notebook or LIMS.

Use aseptic technique, calibrated pipettes or syringes, and validated diluent choices for the assay system. Reconstituted materials should be aliquoted where appropriate to reduce repeated freeze-thaw exposure.

Storage

Store unopened material according to the stated condition: Room temperature, protected from light. Keep vials sealed, dry and protected from light. Reconstituted solutions should be stored under validated laboratory conditions and discarded according to internal SOPs and applicable research-waste rules.

Research-use statement

Tesofensine 5 mg is sold by Peptide Shop for research use only. It is not a medicine, food, cosmetic, supplement or diagnostic product. Buyers are responsible for ensuring lawful purchase, storage, handling and disposal under their institutional and local requirements.

Sequence & data

Product IDpeptide-tesofensine
CAS402856-42-2
Molecular weight382.5 g/mol
Purity≥ 99%

Storage & handling

Room temperature, protected from light

Keep lyophilised material sealed and protected from moisture. Reconstituted materials should be handled according to validated laboratory protocols and disposed of as research waste.

Certificate of analysis

Batch-specific COA documentation is supplied according to the COA policy and may include HPLC purity, identity and lot information where available.

Other languages

FAQs

What is Tesofensine used for in research?

Tesofensine is used in neuroscience and obesity research to study triple monoamine reuptake inhibition. It blocks reuptake of norepinephrine, dopamine, and serotonin, enabling research into appetite regulation and energy expenditure mechanisms.

How does Tesofensine differ from traditional appetite suppressants?

Tesofensine inhibits reuptake of three neurotransmitters (NE, DA, 5-HT) rather than primarily affecting one system. This triple mechanism enables research into complex monoaminergic appetite regulation.

What was Tesofensine originally developed for?

Tesofensine was initially investigated in Parkinson's and Alzheimer's disease research programs. Body-weight observations in trials led to further metabolic-research applications.

How should Tesofensine be stored?

Store Tesofensine at room temperature, protected from light and moisture. Unlike peptides, it doesn't require cold storage. Keep in a cool, dry place.

What purity is your Tesofensine?

Our Tesofensine is ≥99% pure as verified by HPLC analysis. Each batch includes a Certificate of Analysis with purity and identity confirmation.

What is the mechanism of action?

Tesofensine inhibits presynaptic reuptake of norepinephrine, dopamine, and serotonin, increasing synaptic concentrations of these neurotransmitters to affect appetite, satiety, and energy expenditure.

How do I prepare Tesofensine for research?

Tesofensine can be dissolved in DMSO or appropriate organic solvents for in vitro research. Consult literature for specific research application protocols.

What sizes are available?

Tesofensine is available in 10mg and 25mg sizes for various research scales.

What is tesofensine?

Tesofensine is a serotonin-noradrenaline-dopamine reuptake inhibitor (SNDRI) originally developed for neurological research. It is studied in weight management research as a monoamine reuptake inhibitor affecting appetite and metabolism. CAS number 457657-66-8.

Why is tesofensine supplied as 0.5 mg capsules?

Tesofensine is highly potent; in-vivo research doses are typically in the microgram-to-low-milligram range per kilogram. The 0.5 mg/capsule format (60 capsules = 30 mg total) matches standard dosing for metabolic research in animal models.

Is tesofensine a peptide?

Tesofensine is not a peptide. It is a small-molecule piperidine compound. Peptide Shop includes it in its research catalogue because it is commonly used alongside GLP-1 and metabolic peptide research workflows.

What is the CAS number for tesofensine?

Tesofensine CAS number: 457657-66-8. Molecular formula: C17H22ClNO·HCl. Molecular weight: 319.23 g/mol (free base).