Description
Autocamtide-2-related Inhibitory Peptide (AIP) — 1 mg, ≥98 % HPLC — research overview
AIP (Autocamtide-2-related Inhibitory Peptide) is a highly selective Ca²⁺/calmodulin-dependent protein kinase II (CaMKII) inhibitor derived from the autoregulatory domain of the kinase. It is the reference CaMKII inhibitor in cell-signalling research.
Peptide Shop supplies AIP (CaMKII inhibitor) (1 × 1 mg vial) as a sealed research material with lot-level documentation. This product is supplied for in-vitro laboratory research only and is not intended for human use, veterinary use, therapy, diagnosis, cosmetic application or consumption.
Research applications
- In-vitro CaMKII inhibition (IC50 ≈ 40 nM)
- Synaptic plasticity and LTP/LTD research
- Cardiac CaMKII research models
- Reference inhibitor for CaMKII-selective small-molecule screens
Sequence and analytical data
Identity confirmed by ESI-MS. Highly water-soluble; cationic — use low-binding tubes.
Storage and handling
Store lyophilised at -20 °C. Aqueous stocks at -80 °C; avoid freeze-thaw.
Documentation
A lot-specific Certificate of Analysis is available in EN, DE, FR and ES from the product detail page after dispatch. The CoA reports HPLC purity, identity confirmation, appearance, and storage and handling guidance for the dispatched lot.