Description
PKI (6-22) amide — 1 mg, ≥98 % HPLC — research overview
PKI (6-22) amide is the active fragment of the heat-stable protein-kinase inhibitor (PKI), a highly specific competitive inhibitor of cAMP-dependent protein kinase (PKA) catalytic subunit. It is the standard reference inhibitor in kinase-pathway research.
Peptide Shop supplies PKI (6-22) amide (1 × 1 mg vial) as a sealed research material with lot-level documentation. This product is supplied for in-vitro laboratory research only and is not intended for human use, veterinary use, therapy, diagnosis, cosmetic application or consumption.
Research applications
- PKA inhibition in in-vitro kinase assays (Ki ≈ 1–3 nM)
- cAMP / PKA signalling pathway dissection
- Permeabilised-cell PKA inhibition research
- Reference control for PKA-selective small-molecule screens
Sequence and analytical data
C-terminal amidation and identity confirmed by ESI-MS. Highly soluble in aqueous buffers.
Storage and handling
Store lyophilised at -20 °C. Aqueous stock solutions are stable at -80 °C; avoid repeated freeze-thaw.
Documentation
A lot-specific Certificate of Analysis is available in EN, DE, FR and ES from the product detail page after dispatch. The CoA reports HPLC purity, identity confirmation, appearance, and storage and handling guidance for the dispatched lot.
