Description
Semaglutide 5 mg research overview
Semaglutide GLP-1 analogue for metabolic research. ≥99% HPLC purity, sealed vial and lot COA. RUO.
Semaglutide is a long-acting GLP-1 receptor agonist analogue used to study incretin signalling, glucose homeostasis and appetite-regulation pathways.
Peptide Shop supplies Semaglutide 5 mg as a sealed research material with lot-level documentation where available. This product is supplied for in-vitro laboratory research only and is not intended for human or veterinary diagnostic, therapeutic, cosmetic or consumption purposes.
Research use
- GLP-1 receptor activation and downstream signalling
- Insulin secretion and glucagon regulation models
- Metabolic, satiety and gastric-emptying research
Compare with tirzepatide, retatrutide and cagrilintide on the diabetes and metabolism hub.
Sequence and analytical data
| Field | Detail |
|---|---|
| Product ID | peptide-semaglutide |
| Package size | 1 × 5 mg vial |
| CAS number | 910463-68-2 |
| Molecular weight | 4113.58 g/mol |
| Purity | ≥ 99% |
| Storage | -20°C recommended (research-only) |
Batch-specific documentation may include HPLC purity, identity confirmation and lot information. Refer to the supplied COA or the COA policy for current documentation scope.
Reconstitution and handling
Allow lyophilised material to equilibrate before opening to reduce condensation risk. Add validated solvent slowly down the vial wall, avoid vigorous shaking, and record the final concentration in the laboratory notebook or LIMS.
Use aseptic technique, calibrated pipettes or syringes, and validated diluent choices for the assay system. Reconstituted materials should be aliquoted where appropriate to reduce repeated freeze-thaw exposure.
Storage
Store unopened material according to the stated condition: -20°C recommended (research-only). Keep vials sealed, dry and protected from light. Reconstituted solutions should be stored under validated laboratory conditions and discarded according to internal SOPs and applicable research-waste rules.
Related resources
Research-use statement
Semaglutide 5 mg is sold by Peptide Shop for research use only. It is not a medicine, food, cosmetic, supplement or diagnostic product. Buyers are responsible for ensuring lawful purchase, storage, handling and disposal under their institutional and local requirements.
References
- Lau J et al. “Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide.” J Med Chem. 2015;58(18):7370–7380. PMID 26308095
- Marso SP et al. “Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.” N Engl J Med. 2016;375(19):1834–1844. PMID 27633186
- Gabery S et al. “Semaglutide lowers body weight in rodents via distributed neural pathways.” JCI Insight. 2020;5(6):e133429. PMID 32213704
- Blundell J et al. “Effects of once-weekly semaglutide on appetite, energy intake, energy expenditure, gastric emptying, and blood glucose in subjects with obesity.” Diabetes Obes Metab. 2017;19(9):1242–1251. PMID 28266779
- Wilding JPH et al. “Once-Weekly Semaglutide in Adults with Overweight or Obesity.” N Engl J Med. 2021;384(11):989–1002. PMID 33567185
